coronavirus symptoms new york times

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  • Nov 27, 2019

What Are the Symptoms of a Coronavirus Infection? - The New York Times
What Are the Symptoms of a Coronavirus Infection? – The New York Times

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A study of more than 2,000 children with the virus in China found that babies who are very susceptible to developing a severe infection.

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coronavirus rampage across the world have tended to tread softly with children, which explains the infections identified so far.

Now, the largest study to date of children and the virus has been found that while the majority experienced mild or moderate symptoms, a small percentage – particularly infants and preschool children -. can become seriously ill

, published online in the journal Pediatrics, saw more than 2,000 sick children across China, where the pandemic began. This gives a clearer portrait of how the youngest patients affected by the virus, the knowledge that experts say could help influence policies such as closing schools, hospitals and deployment readiness eventual treatment and vaccines.

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researchers analyzed 2,143 cases of children under 18 were reported to the Chinese Center for Disease Control and Prevention February 8. Just over a third of the cases were confirmed by laboratory testing. The remainder is classified as a suspect case based on the child’s symptoms, chest X-rays, blood tests and whether the child had been exposed to people with coronavirus.

About half of the children had mild symptoms, such as fever, fatigue, cough, congestion and possibly nausea or diarrhea. More than a third – 39 percent – became quite ill, with additional symptoms including pneumonia or lung problems revealed by CT scan, but with no obvious shortness of breath. , About 4 percent had no symptoms at all

But there are 125 children – nearly 6 percent-who develop the disease very seriously, and one boy aged 14 years with the infection of coronavirus was confirmed dead, said Shilu Tong, the study’s senior author, who is the director of the department of clinical epidemiology and biostatistics at the Shanghai Children’s Medical Center. Thirteen of them were deemed “critical,” on the verge of respiratory failure or organ. The others are classified as ‘severe’ because they have breathing problems were terrible.

“Effectively, what this tells us that the hospital should prepare for some pediatric patients because we can not rule out the kids at all, “said Dr. Srinivas Murthy, an associate professor of pediatrics at the University of British Columbia, who was not involved in the study.

” main conclusions, “Dr. Murthy continued,” is that children infected at a rate that may be comparable to adults, the severity is much less, but it was even in children, there is a spectrum of disease and there are some that require more therapy aggressive. “

more than 60 percent of the 125 children who are seriously ill or critically ill is age 5 or younger, the study reported. Forty of them a dalah baby under 12 months.

Dr. Tong said he believed that young children are more susceptible to infections because the respiratory system and other body functions quickly developed.

Dr. Andrea Cruz, a professor of pediatrics at Baylor College of Medicine and co-author of the study, says that preschoolers and infants is likely to get sick because they are “immature immune system.”

“They haven ‘t been exposed to the virus before and therefore they are not able to mount an effective immune response,” he said in an interview.

Scientists are actively trying to determine why so many children seem to have emerged relatively unscathed by the new coronavirus, a pattern that also marked the previous outbreak of the SARS virus is closely related to China and Mers in the Middle East. Cases of children with the new coronavirus infection in Italy, Singapore and South Korea appear to be similar, said Dr. Murthy

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A theory that gain increasing currency is that the receptors or proteins in human cells that bind virus particles, so-called, is not expressed as prominent in children or perhaps a different form, Dr. Murthy said.

“This may not be as developed in children as in adults,” he said, which may make it more difficult to nail the viral particles small to bind and gain entry into the cells so that the virus can replicate ,

Another theory is that “most children have healthy lungs” than adults, said Dr. Cruz. Adults are more likely exposed to more pollution than their lifetime and adults with severe coronavirus disease tend to have underlying medical conditions or a weakened immune system or the aging process.

It’s also possible, experts say, that the immune system of children does not rev to attack the virus as much as the immune system of adults do. Doctors have found that some serious damage to infected adults have suffered has been caused not only by the virus itself, but with an aggressive immune response that creates a destructive inflammation in the body’s organs.

The new study, while large and includes cases in China, not only where the outbreak originated in Wuhan, leaves many questions unanswered. For example, the researchers found that more than a severe and critical cases were in children suspected – not a confirmed – coronavirus infection, raising the possibility that other infections wreak havoc on their bodies, in addition to or even might not Covid-19.

It is also unclear whether the United States can expect a relatively small number of reported cases of children in China or should brace for more.

“pyramid age in China is completely different from the US – they have children who are much less than we do,” said Dr. Cruz, who believe, as other experts do, that a large number of people with mild or asymptomatic disease has not been recorded because the test was not carried out in those cases. “You’ve been a lot of under-testing in children because it has focused on adults. It may be we have underestimated the burden of disease in children. “

Asked about the coronavirus in children could reverberate well beyond the pediatric population. This could explain why some patients are most at risk. And, said Dr. Murthy, studying the physiology of those less affected can assist in the development of treatments and vaccines.

Updated March 17, 2020

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