hantavirus seoul virus

  • 6 min read
  • Mar 27, 2020

Experts Respond to Seoul Virus Cases - Veterinary Medicine at Illinois
Experts Respond to Seoul Virus Cases – Veterinary Medicine at Illinois

Yes. Seoul virus is a member of the hantavirus family of rodent-borne virus. This family also includes the Sin Nombre virus, hantavirus most common causes of this disease in the United States. Most hantaviruses have only one or two species of rodents as their natural host. For Seoul virus, the natural host is the Norway rat (Rattus norvegicus) and the black rat (Rattus rattus), while for Sin Nombre the deer mouse (Peromyscus maniculatus). In mice that carry them, this virus does not cause disease, but it did cause a lifelong infection and viral shedding. This virus sometimes can be transmitted to other species of rodents, but they do not cause chronic infection and shedding virus.

severe disease associated with infection of Sin Nombre virus called hantavirus pulmonary syndrome (HPS). Most HPS infection causes fever and body aches, developed severe breathing difficulties that often require hospitalization. Death occurs in about 38% of cases (or 38 out of every 100 patients). Conversely, severe illness associated with Seoul virus is dengue fever with renal syndrome (HFRS). Most people who are infected with the virus experience mild Seoul or even no symptoms. However, the severe form of the disease, patients can indicate bleeding and kidney involvement, and death occurs in approximately 1-2% of cases (or 1-2 out of every 100 people sick).

CDC working with state health departments and others to investigate an outbreak of a viral infection in rodents Seoul pets and humans. delivery of CDC and its partners explore and transport rats, some of which are infected with Seoul virus, to better understand how the virus enters the pet trade, and to interrupt transmission of the virus Seoul to other mice or people.

Meanwhile, Seoul virus infection in humans is generally considered to be less severe than some other types of hantavirus infection, they can cause severe illness in some cases. Some people may develop a severe form of the infection known as hemorrhagic fever with renal syndrome (HFRS), and an estimated 1-2% of people infected with the virus may die after Seoul. Since there is currently no effective treatment for viral infections Seoul, to prevent infection in people who are important.

Seoul virus diagnostic tests can be performed on living mice by taking a small blood sample and test it in the laboratory. Rats do not have to euthanasia to collect blood samples. Blood samples sent to CDC or to another laboratory to perform diagnostic tests for viral infections Seoul. CDC and other laboratories perform tests look for antibodies (serology) and / or evidence of viral genetic material [by polymerase chain reaction (PCR)]. A positive result means that the mice had been infected with the virus Seoul and considered to pose the risk of transmitting the virus to other mice, or to the people. infected mice is believed to remain infectious for life with a permanent or intermittent virus shedding. A negative result means there is no evidence of Seoul virus infection in mice at the time of sampling.

State and local health departments to reach the breeder and owner of mice from suspected or confirmed facilities. The team worked with the state department of health will visit the facility suspected, and, working with owner-will take a blood sample for testing. Owner mice that were not associated with the facility confirmed but who want their mice to be tested can choose to do it independently through commercial laboratories.

Yes. Some commercial laboratories offer testing for viruses Seoul. The IDEXX * serology (antibody) test (Opti-Spot ™) and molecular testing (PCR) for Seoul virus in mice yielded results that are closely similar to those for the CDC test for Seoul virus in mice. The Charles River Laboratories serological test (EZ-Spot®) currently being validated by the CDC. CDC will continue to work with Charles River Laboratories IDEXX and to compare the results of serological and molecular Seoul virus. CDC continues to inform the health department in the countries affected by the findings and will reach rat animal owners and breeders through clubs, forums, and conference calling. Serological and molecular testing newly arrived mice can be an effective tool to prevent the entry of infected mice in uninfected colonies. The owners and breeders may want to look for evidence of this rodent infection status before admitting new animals intoexisting colonies.

* Name of the commercial companies that provided for information purposes only and does not constitute an endorsement by CDC or the Department of Health and Human Services.

serology test is the most accurate and sensitive for Seoul virus. Accuracy PCR testing as a screening tool has not been set. Thus, the negative results of PCR tests of blood, urine, fecal pellets, bedding, or organ should not be construed that the mice not infected Seoul.

Seoul virus is kind. People infected with this virus often show relatively mild or no disease but some will develop a form of death in approximately 1-2% of cases (1 to 2 in 100 people).

Seoul virus is found worldwide. It is carried and spread by rodents, especially brown or Norway rat (Rattus norvegicus). The virus has been found in a pet rat and wild rat populations around the world.

People can be infected with this virus after coming in contact with urine, droppings, or saliva of infected rodents. When rats fresh urine, droppings, or nesting material stirred up (for example, when dust or sweep), tiny particles containing the virus get into the air. This process is known as “aerosolization”. You can get infected when you inhale contaminated materials. You can also become infected when urine or other material that contains a virus to get directly to wounds or other damaged skin or to the eyes, nose, or mouth. In addition, people who work with live rodents can get Seoul virus through the bite of an infected animal.

Seoul virus is not known to spread from person to person.

If you are infected with a virus Seoul, you may have the following symptoms:

symptoms of diseases caused by viruses Seoul usually begin within 1 to 2 weeks after contact with infectious material. Rarely, it can take up to 8 weeks to develop symptoms.

In rare cases, infection can also cause a type of kidney disease called dengue acute renal syndrome (HFRS), which may include low blood pressure, shock, acute and acute renal failure. However, Seoul virus infection is usually moderate and most patients survive. Full recovery can take weeks or months. Some people experience no symptoms at all or have very mild symptoms.

Several laboratory tests of blood and tissue were used to confirm the diagnosis of Seoul virus infection in patients suspected of having the infection.

supportive care given to patients with viral infections Seoul. Treatments include fluid therapy with fluids directly into patients’ blood vessels to maintain blood volume, blood pressure, and electrolytes (sodium, potassium, chloride) levels. Oxygen masks can also be used as well as the appropriate treatment of secondary infections. Dialysis may be required in severe cases of kidney failure. Ribavirin, an antiviral drug, has been shown to reduce the severity of disease and lower mortality associated with viral infections Seoul if used very early in the disease.

Avoid contact with rodents and rodent control is the key to prevent virus infection Seoul. Rodents near human communities must be controlled, and rats must be removed from the home. You should avoid contact with rat urine, feces, saliva, and nesting material. It is important to know.

Seoul virus is shed in the urine, feces, and saliva newly infected mice. Mice can be infected with Seoul virus through biting injure or other rat and after coming in contact with urine and feces of infected mice.

mice did not show symptoms when they are infected with Seoul. Mice which may come from a facility where mice have been confirmed with the infection can be tested for evidence of viral infection in the laboratory. Once infected, the mice can continue to shed the virus throughout their lives, both potentially infect other mice and humans.

If you have any questions, you can call the CDC-INFO at 800-CDC -INFO (800-232-4636), TTY :. 888-232-6348 or

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